Medicinal Chemistry

Medicinal Chemistry

Lead compounds discovery/optimization

Lead compound is a compound with certain biological activity and chemical structure obtained by various ways and means for further structural modification and optimization, which is the starting point of modern new drug research.
  • Structure-activity relationship driven
  • Compound library driven
  • ADME/DMPK properties driven
  • Physicochemical properties driven
  • Safety and toxicity driven
  • Key compound/intermediate scale-up
Lead compound optimization is the process of optimizing other defective properties while maintaining some of the excellent properties of the lead compound. The goal of optimizing a lead compound is to produce one or more preclinical candidate compounds. PharmaResources can provide a variety of services such as pharmacochemical research, computer aided drug design, compound synthesis and scale-up.
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